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Asahi Ito Selected Research

mogamulizumab

10/2022Genomic determinants impacting the clinical outcome of mogamulizumab treatment for adult T-cell leukemia/lymphoma.
1/2022Clinical significance of the immunoglobulin G heavy-chain repertoire in peripheral blood mononuclear cells of adult T-cell leukaemia-lymphoma patients receiving mogamulizumab.
1/2021Clinical significance of CD28 gene-related activating alterations in adult T-cell leukaemia/lymphoma.
1/2021Immunohistochemistry for CCR4 C-terminus predicts CCR4 mutations and mogamulizumab efficacy in adult T-cell leukemia/lymphoma.
10/2020Mogamulizumab for adult T-cell leukemia-lymphoma: a multicenter prospective observational study.
1/2020Robust CD8+ T-cell proliferation and diversification after mogamulizumab in patients with adult T-cell leukemia-lymphoma.
1/2019Mogamulizumab Treatment Elicits Autoantibodies Attacking the Skin in Patients with Adult T-Cell Leukemia-Lymphoma.
1/2018CCR4 mutations associated with superior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment.
4/2015Reactivation of hepatitis B virus (HBV) infection in adult T-cell leukemia-lymphoma patients with resolved HBV infection following systemic chemotherapy.
5/2013Stevens-Johnson Syndrome associated with mogamulizumab treatment of adult T-cell leukemia / lymphoma.

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Asahi Ito Research Topics

Disease

19Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
10/2022 - 02/2009
19Neoplasms (Cancer)
01/2022 - 11/2008
13Multiple Myeloma
06/2020 - 11/2008
7Lymphoma (Lymphomas)
01/2022 - 06/2010
4Hepatitis
09/2022 - 06/2010
3Infections
09/2022 - 04/2015
3Hematologic Neoplasms (Hematological Malignancy)
09/2022 - 09/2016
2Disease Progression
01/2022 - 01/2021
2Leukemia
12/2018 - 03/2012
1Inflammation (Inflammations)
03/2022
1Crohn Disease (Crohn's Disease)
03/2022
1Genomic Instability
03/2022
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
12/2020
1Back Pain (Backache)
06/2020
1Lymphopenia (Lymphocytopenia)
01/2020
1Chromosome Aberrations (Chromosome Abnormalities)
08/2019
1Communicable Diseases (Infectious Diseases)
08/2019
1Fever (Fevers)
08/2019
1Fungemia
08/2019
1Pleural Effusion (Pleural Effusions)
07/2019
1Primary Myelofibrosis (Myelosclerosis)
07/2019
1Blast Crisis (Blast Phase)
07/2019
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
07/2019
1Hemorrhagic Cystitis
01/2019
1Erythema Multiforme
01/2019
1Large Granular Lymphocytic Leukemia
12/2018
1Extranodal NK-T-Cell Lymphoma
12/2018
1Exanthema (Rash)
01/2018
1Dyspnea (Shortness of Breath)
01/2018
1Hodgkin Disease (Hodgkin's Disease)
01/2018
1Hypothyroidism
01/2018
1Monoclonal Gammopathy of Undetermined Significance
01/2018
1Paraproteinemias (Monoclonal Gammopathy)
01/2018
1Respiratory Insufficiency (Respiratory Failure)
01/2018
1Nemaline Myopathies (Nemaline Myopathy)
01/2018
1Rare Diseases (Rare Disease)
01/2018
1Hepatocellular Carcinoma (Hepatoma)
09/2016
1Liver Cirrhosis (Hepatic Cirrhosis)
09/2016
1Amyloidosis
01/2016
1Immunoglobulin Light-chain Amyloidosis
01/2016

Drug/Important Bio-Agent (IBA)

10mogamulizumabIBA
10/2022 - 05/2013
8Monoclonal AntibodiesIBA
01/2020 - 08/2009
6Bortezomib (Velcade)FDA Link
06/2020 - 11/2008
6Dexamethasone (Maxidex)FDA LinkGeneric
04/2020 - 03/2016
6Proteins (Proteins, Gene)FDA Link
12/2018 - 07/2009
4DNA (Deoxyribonucleic Acid)IBA
09/2022 - 06/2010
4Tryptophan (L-Tryptophan)FDA Link
12/2020 - 06/2015
4Lenalidomide (CC 5013)FDA Link
04/2020 - 04/2013
4Rituximab (Mabthera)FDA Link
01/2012 - 07/2009
3Immunoglobulin G (IgG)IBA
01/2022 - 01/2018
3Proteasome InhibitorsIBA
02/2018 - 02/2009
2Biomarkers (Surrogate Marker)IBA
10/2022 - 09/2022
2AntigensIBA
09/2022 - 03/2012
2Hepatitis B Surface Antigens (HBsAg)FDA Link
09/2022 - 06/2010
2LigandsIBA
01/2022 - 07/2009
2Complement System Proteins (Complement)IBA
01/2019 - 12/2010
2Cyclin-Dependent Kinase 9IBA
12/2018 - 01/2017
2atuveciclibIBA
12/2018 - 01/2017
2Bevacizumab (Avastin)FDA Link
03/2014 - 01/2012
2Messenger RNA (mRNA)IBA
12/2013 - 03/2012
1A-factor (Streptomyces)IBA
03/2022
1Azathioprine (Imuran)FDA LinkGeneric
03/2022
1entecavirFDA Link
06/2020
1Melphalan (Alkeran)FDA LinkGeneric
06/2020
1NucleotidesIBA
06/2020
1Prednisolone (Predate)FDA LinkGeneric
06/2020
1daratumumabIBA
06/2020
1Voriconazole (Vfend)FDA LinkGeneric
08/2019
1AntibodiesIBA
07/2019
1ponatinibIBA
07/2019
1Dasatinib (BMS 354825)FDA Link
07/2019
1Signaling Lymphocytic Activation Molecule FamilyIBA
07/2019
1Surface Antigens (Surface Antigen)IBA
07/2019
1AutoantibodiesIBA
01/2019
1Immunoglobulin M (IgM)IBA
01/2019
1RNA Polymerase II (RNA Polymerase B)IBA
12/2018
1Serine (L-Serine)FDA Link
12/2018
1afuresertibIBA
06/2018
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
06/2018
1pomalidomideIBA
06/2018
1Proteasome Endopeptidase Complex (Proteasome)IBA
02/2018
1TrypsinIBA
02/2018
1ChymotrypsinFDA Link
02/2018
1Thalidomide (Thalomid)FDA Link
01/2018
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
01/2018
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2018
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
01/2018
1Interleukin-2 Receptors (IL 2 Receptor)IBA
01/2017
1Positive Transcriptional Elongation Factor BIBA
01/2017
1wisteria lectinIBA
09/2016
1Immunomodulating AgentsIBA
03/2016

Therapy/Procedure

11Drug Therapy (Chemotherapy)
09/2022 - 06/2010
11Therapeutics
04/2020 - 01/2006
4Immunotherapy
11/2015 - 03/2012
3Hematopoietic Stem Cell Transplantation
07/2019 - 04/2013
2Stem Cell Transplantation
01/2018 - 06/2010
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
07/2019
1Drug Tapering
01/2019
1Positive-Pressure Respiration (Positive End-Expiratory Pressure)
01/2018
1Artificial Respiration (Mechanical Ventilation)
01/2018